The Safety and Efficacy of Phentolamine Mesylate Ophthalmic Solution in Subjects With Severe Night Vision Disturbances
Status:
Completed
Trial end date:
2012-04-30
Target enrollment:
Participant gender:
Summary
The objectives of this study are:
- To evaluate the efficacy of phentolamine mesylate 0.5% and 1.0% ophthalmic solution
(Nyxol) in the treatment of night vision complaints, including reduced contrast
sensitivity
- To evaluate the ocular and systemic safety of phentolamine mesylate 0.5% and 1.0%
ophthalmic solution (Nyxol) compared to its vehicle, a sterile, isotonic, buffered
aqueous solution containing mannitol and sodium acetate