The Study of Mindfulness Based Cognitive Therapy and Obsessive-Compulsive Disorder

• Status: Completed
• Trial end date: 2019-07-20
• Target enrollment: 0
• Participant gender: All

Summary

The primary objective of the study is to evaluate the clinical curative effect of MBCT to reduce obsessive and compulsive symptoms. Moreover, the investigators will also explore a MBCT manual for Chinese patients with OCD, which can be widely applied to the clinical practice.

There are two parts of the study. The first part is a qualitative research with two pilot MBCT groups. The second part of this study is a single-blind randomized controlled trial with three study arms: one - third of participants receive group mindfulness-based cognitive therapy led by trained MBCT psychotherapists or psychiatrists in addition to medication, one

• third of participants receive group psycho-education program and one - third of participants receive drug therapy as usual. All participants have 10 sessions intervention and assessments.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shanghai Mental Health Center
• Treatments: Fluvoxamine; Sertraline

Criteria

Inclusion Criteria:

• Participants should suffer from clinically OCD symptoms and have a DSM-IV Axis Ⅰ diagnosis of OCD (M.I.N.I.)

• 12≤ Y-BOCS score ≤25

• Male or female, 18 years old to 54 years of age

• Junior middle school education or above

• Have not yet accepted psychiatric medication, or had received irregular medication treatment and have been discontinued 8 weeks

• Have enough visual and acoustic ability to complete the inspection required for the study

• Each patient and his guardian must understand the nature of this study and sign the informed consent form

Exclusion Criteria:

• meet DSM-IV Axis Ⅰ diagnostic criteria for other psychiatric disorders

• persons with severe physical disease or central nervous system disease

• have a strong negative concept or a high risk of suicide

• substance abuse, pregnancy or the preparation of recently pregnant women and lactating women

• severe obsessive compulsive symptoms, so that patients can not complete the required assessment and treatment intervention

• at the same time to accept MECT or other psychological therapy

• patients had previously received treatment of mindfulness-based intervention, and no significant effect