The Study to Evaluate Efficacy and Safety of Candesartan vs Losartan in Hypertension With Heart Failure (HONOR)

• Status: Terminated
• Trial end date: 2014-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare efficacy and safety of candesartan and losartan in hypertension with heart failure.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chong Kun Dang Pharmaceutical
• Treatments: Candesartan; Candesartan cilexetil; Losartan

Criteria

Inclusion Criteria:

• Female and male patients who aged above 19 and below 75

• Patients with 90~109mmHg average sitting DBP on baseline

• NYHA class 2~4

• Patients who agreement with written informed consent

Exclusion Criteria:

• above 110mmHg sitting DBP and/or 180mmHg sitting SBP

• Patients who have difference values that above 20mmHg sitting SBP or 10mmHg sitting DBP in both arms on screening

• Patients who have medical history that secondary hypertension or rule out secondary hypertension

• malignant hypertension

• symptomatic postural hypotension

• right heart failure due to pulmonary disease

• etc.