The T REX Pilot Study: a Study to Investigate the Use of an Alternative Anaesthetic in Infants.
Status:
Completed
Trial end date:
2016-09-01
Target enrollment:
Participant gender:
Summary
Animal studies suggest general anaesthetics harm the developing brain. It is unclear if these
findings are relevant to humans but the issue has become a major concern. Recent data have
found that monkeys exposed to anaesthesia as infants grow up to have slower learning than
those not exposed.
The aim of the TREX pilot study is to determine the feasibility of an alternative anaesthetic
regimen for lower abdominal/lower extremity surgery in infants 1-12 months of age.
Phase:
Phase 4
Details
Lead Sponsor:
Murdoch Childrens Research Institute
Collaborators:
Baylor College of Medicine Boston Children's Hospital Boston Children’s Hospital Children's Hospital Medical Center, Cincinnati Children's Hospital of Philadelphia Gaslini Children's Hospital KK Women's and Children's Hospital Oregon Health and Science University Princess Margaret Hospital for Children Starship Children's Health Sydney Children's Hospitals Network Sydney Children's Network Texas Children's Hospital The Cleveland Clinic The Royal Children's Hospital Melbourne UMC Utrecht University Hospital, Geneva University of Texas Southwestern Medical Center