The Therapeutic Effect of Dau-Di-Wu-Gong in Patient With Ankle Fracture

• Status: Completed
• Trial end date: 2021-01-11
• Target enrollment: 0
• Participant gender: All

Summary

Ankle fracture is one of most common bone fracture in Taiwan, although ankle fracture can be treated by surgical operation, local edema, pain and wound poor healing always is noted, according to the investigator's knowledge, no good therapeutic methods to treat mention-above symptoms until now. Helminthostachys zeylanica(L.)Hook, also called Dau-Di-U-Gon has anti-inflammation, calm down heat and detoxication, and anti-edema. People in Taiwan often uses Helminthostachys zeylanica(L.)Hook to treat bone and tendon pain, and its Ugonin component of Helminthostachys zeylanica(L.)Hook also is proved that has analgesia and ant-inflammation. Therefore, the purpose of the present study was to design a randomized, double-blind, controlled study to evaluate functional recovery effect of Helminthostachys zeylanica(L.)Hook after surgical operation in patients with ankle fracture.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Changhua Christian Hospital

Criteria

Inclusion Criteria:

• 20-75 year-old male or female with acute ankle fractures with surgical indication (Joint line displacement >2mm ; fracture dislocation)

Exclusion Criteria:

• Previous skin disease, DM or peripheral vessel disease with local foot amputation.

• Previous ankle surgery, old ankle fracture, or open fracture.

• Liver or renal dysfunction, and cardiorespiratory failure.

• Surgical infection after surgery.

• Patient refuse or can't finish the treatment course

• Patient with cancer

• Pregnancy

• HIV positive.