The Use of FLOSEAL to Reduce Bleeding in Total Knee Replacement Surgery

• Status: Completed
• Trial end date: 2010-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if the agent, Floseal, can decrease the amount of blood patients lose after total knee replacement (TKR) surgery. If this product can be found to have an effect on bleeding, it may potentially reduce the problems associated with bleeding after knee replacement surgery such as pain, stiffness, and the need to have a blood transfusion. The subject's overall participation will be over a period of 6 weeks.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital for Special Surgery, New York
• Collaborator: Baxter Healthcare Corporation
• Treatments: Hemostatics; Thrombin

Criteria

Inclusion Criteria:

• Single Knee replacement for arthritis of the knee

Exclusion Criteria:

• No inflammatory arthritis (ie. Rheumatoid arthritis)

• No allergies to cow meat (bovine allergies

• No history of bleeding disorders