The Use of Fibrin Sealant to Reduce Bleeding After Total Knee Replacement
Status:
Completed
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
A randomized controlled study is performed to address the question of whether the topical
application of a novel fibrin sealant, Evicel (Johnson & Johnson Wound Management, Ethicon,
Somerville, NJ) in patient undergoing total knee replacement (TKR) reduce the perioperative
blood loss and the need for allogenic blood transfusion compared to a control group. We
hypothesize that fibrin sealant decrease the drop in post-operative hemoglobin level after
total knee replacement.