The Use of GnRH Agonist Trigger in the Prevention of OHSS

• Status: Completed
• Trial end date: 2006-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

To compare the incidence of ovarian hyperstimulation syndrome (OHSS) and implantation rate between high responder patients using Gonadotropin releasing GnRH) agonist or human chorionic gonadotropin (hCG) to trigger final oocyte maturation.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Connecticut
• Collaborator: Organon
• Treatments: Deslorelin; Leuprolide

Criteria

Inclusion Criteria:

• age 20-39

• normal early follicular phase serum FSH (≤10.0 IU/l)

• patients with either PCOS or PCOM undergoing their first cycle of IVF or patients with high response in a previous IVF cycle.

Exclusion Criteria:

• Hypogonadotropic hypogonadism