The Use of Intranasal Fentanyl for the Treatment of Incident Dyspnea in Congestive Heart Failure: A Prospective Trial

• Status: Completed
• Trial end date: 2017-09-15
• Target enrollment: 0
• Participant gender: All

Summary

Study Objective The primary object of this study is to investigate the safety and effectiveness of fentanyl on the management of incident dyspnea.

Study Design The study design will be a cross over study with a minimum of a one hour wash out period.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: St. Boniface General Hospital Research Centre; St. Boniface Hospital
• Treatments: Fentanyl

Criteria

Inclusion Criteria:

• Patients must be experiencing activity-induced incident dyspnea without reversible causes. They would have controlled background dyspnea without opioids.

• Patients must be physically able to safely ambulate in order to complete the 6MWT (may have mobility devices and may use supplement oxygen prescribed pre-study).

Exclusion Criteria:

• Patients who are unable to perform the 6MWT for any reason or have contraindications to performing the 6MWT

• Patients that have anatomical pathologies that would make intranasal administration impossible

• Patients with known allergies/sensitivities to fentanyl/sufentanil