The Use of Ketamine as Rescue Analgesia in the Recovery Room Following Opioid Administration. A Double-blind Randomised Trial in Postoperative Patients

• Status: Completed
• Trial end date: 2004-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This clinical trial will determine if postoperative patients who have postoperative pain, which has been refractory to morphine administration, will have improved pain relief following a bolus administration of ketamine as compared with an ongoing morphine dosing regimen

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bayside Health
• Treatments: Analgesics, Opioid; Ketamine

Criteria

Inclusion Criteria:

• 1. Those patients requiring the routine pain protocol to be implemented as used in the Post Anaesthetic Care Unit who need more than two doses of morphine (and having received intraoperative morphine).

Exclusion Criteria:

• Exclusion Criteria

1. Known allergy to morphine or ketamine.

2. Past history of major psychiatric disturbance or currently taking psychiatric medication/s.

3. Chronic morphine usage.

4. Chronic pain syndrome or chronic painful medical condition.

5. Unable to obtain a reliable pain score in recovery due to language barriers or residual anaesthesia.

6. Known pregnancy.

7. Cases where primary anaesthetist prefers alternate therapy.

8. Aged less than 18 years.

9. Weight less than 50 kilograms or greater than 100 kilograms.

10. Use of ketamine intraoperatively.

11. Use of major regional block.