The Use of Memantine for Prevention of Alzheimer's Disease
Status:
Not yet recruiting
Trial end date:
2023-10-01
Target enrollment:
Participant gender:
Summary
As the US population ages, the prevalence of dementia is increasing, and Alzheimer's Disease
(AD) is the most prevalent one. Solving the Alzheimer's Disease (AD) epidemic is likely to
require preventive therapy beginning many years before symptoms are expected to be evident in
at-risk individuals. AD is caused by the dysfunction, loss of synapses, and eventual neuronal
death, which may occur up to 25 years before clinical symptoms appear. This study, based off
of pre-clinical data, seeks to assess whether it is feasible to use memantine hydrochloride
for the prevention of Alzheimer's Disease.