The Use of Metformin in Early Breast Cancer Patients Pre-Surgery

• Status: Withdrawn
• Trial end date: 2016-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The study will test metformin in patients with early breast cancer. Blood and tissue will be collected before and after the use of metformin.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto Nacional de Cancer, Brazil
• Treatments: Metformin

Criteria

Inclusion Criteria:

• Invasive breast cancer T1 or T2, Nx

• Knowledge of the investigational nature of the study and ability to provide consent for study participation

Exclusion Criteria:

• Diabetes or baseline glucose or Glycosylated haemoglobin upper limit of normal for the institution

• Recent use of corticosteroids

• AST > 1.5 times upper limit of normal for the institution

• Pregnancy

• Serious clinical illness

• Prior or concurrent systemic neoadjuvant Breast Cancer therapy.