The Use of Tranexamic Acid to Reduce Perioperative Blood Loss During High Risk Spine Fusion Surgery

• Status: Completed
• Trial end date: 2017-12-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if tranexamic acid reduces perioperative blood loss and red blood cell transfusion during high risk spine surgery.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Northwestern University
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• age>17 years

• undergoing posterior spine fusion surgery for kyphoscoliosis with a >80% chance of major transfusion

Exclusion Criteria:

• age < 18 years

• non-English speaking

• pregnancy

• emergency procedures

• surgery for tumor, trauma or infection

• severe coronary artery disease

• history of venous thromboembolism

• history of cerebral vascular accident

• history of renal insufficiency

• allergy to tranexamic acid