The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children

• Status: Not yet recruiting
• Trial end date: 2022-03-01
• Target enrollment: 0
• Participant gender: All

Summary

To evaluate the efficacy of Intra-lesional triamcinolone injection in the management of refractory benign esophageal Stricture in children.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Triamcinolone; Triamcinolone Acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide

Criteria

Inclusion Criteria:

• All patients admitted to Assiut University Children Hospital with:

• refractory benign esophageal stricture(inability to successfully remediate the anatomic problem to a diameter of at least 14 mm over five sessions at two-week interval)

• inability to maintain a satisfactory luminal diameter for four weeks once the target diameter of 14 mm has been achieved

Exclusion Criteria:

• Pharyngeal stenosis precluding endoscopic examination and dilatation

• tracheo-esophageal fistula,

• gastric cicatrization that precluded safe placement of aguidewire

• any patient who was unfit for general anesthesia.