The Value of Lymph Node Dissection of Indocyanine Green-guided Near-infrared Fluorescent Imaging in Esophagectomy

• Status: Recruiting
• Trial end date: 2021-10-30
• Target enrollment: 0
• Participant gender: All

Summary

Indocyanine green (ICG) has been recently introduced in clinical practice as a fuorescent tracer. Lymphadenectomy is particularly challenging in esophageal cancer surgery, owing to the complex anatomical drainage.Therefore, the purpose of this study was to explore whether the NIR-ICG imaging system could accurately assess the lymph node markers during radical resection of esophageal cancer.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Fujian Medical University Union Hospital

Criteria

Inclusion Criteria:

1. Age and gender: 18-75 years old, male and female unlimited;

2. Preoperative biopsy was pathologically diagnosed as esophageal squamous cell carcinoma;

3. Preoperative combination with neoadjuvant chemoradiotherapy;

4. Surgical resection of esophageal carcinoma under endoscopic selection and intraoperative anastomosis;

5. Heart, lung, liver and kidney functions can tolerate operation;

6. Patients and their family members can understand and are willing to participate in this clinical study and sign the informed consent.

Exclusion Criteria:

1. Allergic to ICG or iodine;

2. Patients with a history of chest surgery or thoracic lymph node dissection;

3. Patients needing emergency surgery;

4. Patients whose tumors involve neighboring organs and need to be removed by combining organs;

5. Patients with tumor recurrence or distant metastasis;

6. Patients who had participated in or were participating in other clinical trials within the previous 4 weeks were included;

7. A history of serious mental illness;

8. Pregnant or lactating women;

9. Patients with other conditions considered by the researcher should not participate in the study.