Therapeutic Drug Monitoring of Anxiolytics in Children

• Status: Recruiting
• Trial end date: 2022-12-31
• Target enrollment: 0
• Participant gender: All

Summary

In this study, the therapeutic drug monitoring of anxiolytics is carried out among children to obtain the drug concentration, clinical efficacy and safety data of children patients in different gender and age groups. Then the investigators analyze the relationship between blood drug concentration and efficacy and safety, and provide recommendations for the treatment window of anxiolytics in Chinese children.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Wei Zhao
• Treatments: Anti-Anxiety Agents; Diazepam; Midazolam; Propofol

Criteria

Inclusion Criteria:

• Anxiolytics was used for therapeutic purposes;

• Age:≤18 years;

• Patients with therapeutic concentration monitoring of anxiolytics.

Exclusion Criteria:

• Patients without therapeutic concentration monitoring of anxiolytics;

• The blood concentrations of the patient was not approved by the quality control center

• Use foods or products that inhibit or induce CYP 3A activity.