Therapeutic Effect Of Luteolin Natural Extract Versus Its Nanoparticles On Tongue Squamous Cell Carcinoma Cell Line

• Status: Unknown status
• Trial end date: 2019-04-01
• Target enrollment: 0
• Participant gender: All

Summary

In vitro study to examine whether luteolin and nano-luteolin exert an inhibitory effect on tongue squamous cell carcinoma cell line by inducing apoptosis, and to assess if nano-luteolin has more efficient apoptotic activity than luteolin on tongue squamous cell carcinoma cell line.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University

Criteria

Inclusion Criteria:

• Squamous cell carcinoma cell lines (OSCC, TSCC and HNSCC).

• Luteolin 5,7,3',4'-tetrahydroxy-flavone (MeSH term).

• Application of luteolin as a chemotherapeutic drug.

Exclusion Criteria:

• Any cancer cell line other than OSCC, TSCC and HNSCC cell lines.

• Luteolin glycosides.