Therapeutic Effect of Low-dose Prednisone Combined With MMF and FK506 in Focal Segmental Glomerulosclerosis

• Status: Unknown status
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this clinical trial is to determine the effect and security of low-dose Prednisone Combined With MMF and FK506 in Focal Segmental Glomerulosclerosis.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Health Science Center of Xi'an Jiaotong University; Health Science Center of Xi’an Jiaotong University
• Treatments: Prednisone; Tacrolimus

Criteria

Inclusion Criteria:

• Urinary protein≥1.0g/24h

• Biopsy-proved FSGS

• Age≥16years

• Understanding of the content of this study，signing informed consent form

• Adherence to drug taking and being able to be long-term followed up

Exclusion Criteria:

• Sharp deterioration of renal function

• Refractory hypertension

• Secondary FSGS

• Serious disease of liver，active stage of viral hepatitis，or AST、ALT≥2.5 times of baseline

• Serious myelosuppression

• Being unable to be long-term followed up