Therapeutic Modulation of the Intestinal Creatine Kinase System in Inflammatory Bowel Disease (IBD)
Status:
Not yet recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
This study plans to learn more about the effects that creatine monohydrate has on disease
activity in ulcerative colitis. Creatine is a substance that is naturally produced by the
body and is found in foods, such as meat and fish. Creatine helps to provide energy to some
body tissues, such as the colon. In the colon, this energy allows cells to form a tight
barrier between molecules in digested food and bacteria and the body's infection-fighting
cells within the colon underneath this barrier. If the barrier becomes "leaky" molecules may
pass through and lead to inflammation. This "leakiness" may contribute to the colon
inflammation seen in ulcerative colitis.