Overview

Therapy Based on Stage of Disease and Risk Assessment in Treating Children With Neuroblastoma

Status:
Completed
Trial end date:
2003-09-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with bone marrow transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more tumor cells. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which treatment regimen is most effective in treating patients with different stages of and risk factors for neuroblastoma. PURPOSE: Phase III trial to study the effectiveness of therapy based on stage of disease and risk assessment in treating children with neuroblastoma.
Phase:
Phase 3
Details
Lead Sponsor:
Children's Hospital Medical Center, Cincinnati
Treatments:
Carboplatin
Cobalt
Cyclophosphamide
Dacarbazine
Doxorubicin
Etoposide
Ifosfamide
Liposomal doxorubicin
Melphalan
Vincristine
Vindesine