Overview

Therapy of Non-Hodgkin-Lymphoma by Combination of Lenalidomide + Rituximab, Dexa, High-dose ARA-C and CisP

Status:
Terminated
Trial end date:
2015-04-28
Target enrollment:
Participant gender:
Summary
The goal of this study is to evaluate efficacy and safety of the combination of lenalidomide, an immunomodulatory drug (IMiD) with a standard immunochemotherapy treatment, called R-DHAP. R-DHAP consists of a monoclonal antibody called Rituximab and chemotherapy consisting of Dexamethasone, high dose Cytarabine, often called Ara-C, and platinum based chemotherapy, either cisplatinum, or, if treatment with cisplatinum is contraindicated, carboplatinum.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH
Gesellschaft fur Medizinische Innovation – Hamatologie und Onkologie mbH
Collaborators:
Amgen
Celgene
Treatments:
BB 1101
Carboplatin
Cisplatin
Cytarabine
Dexamethasone
Dexamethasone acetate
Lenalidomide
Rituximab
Thalidomide