Thermosensitive Gels for the Vaginal Delivery of Sildenafil Citrate

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study was to develop and characterize in situ thermosensitive gels for the vaginal administration of sildenafil as a potential treatment of the endometrial thinning that occurs as a result of the use of clomiphene citrate in induction of ovulation in women with World Health Organization type II EU gonadotrophic anovulation.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Citric Acid; Clomiphene; Enclomiphene; Sildenafil Citrate; Zuclomiphene

Criteria

Inclusion Criteria:

• women with polycystic ovaries

Exclusion Criteria:

• women with other causes of infertility