Thoracic Epidural Analgesia Versus Rectus Sheath Block Versus Surgeon Infiltration With Liposomal Bupivacaine or Standard Bupivacaine for Post-Operative Pain Control After Cystectomy

• Status: Recruiting
• Trial end date: 2023-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the difference between four different pain control methods in patients who will be having a cystectomy surgery (surgical removal of the bladder).

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Indiana University
• Treatments: Bupivacaine; Hydromorphone

Criteria

Inclusion Criteria:

• Patients undergoing cystectomy for bladder cancer

• ASA class 1, 2, 3 or 4

• Age 18 or older, male or female

• Desires Regional anesthesia for postoperative pain control

Exclusion Criteria:

• Any contraindication for thoracic epidural.

• History of substance abuse in the past 6 months.

• Patients on more than 30mg morphine equivalents of opioids daily.

• Any physical, mental or medical conditions which in the opinion of the investigators, may confound quantifying postoperative pain resulting from surgery.

• Known allergy or other contraindications to the study medications (Acetaminophen, Gabapentin, Bupivacaine, Hydromorphone).

• Postoperative intubation.

• Any patient with history of neuropathic bowel or bladder dysfunction