Thoracoscopic Sentinel Lymph Node Biopsy in Patients With Stage I or Stage II Breast Cancer

• Status: Completed
• Trial end date: 2011-03-01
• Target enrollment: 0
• Participant gender: All

Summary

RATIONALE: Diagnostic procedures, such as thoracoscopic sentinel lymph node biopsy, may help find breast cancer that has spread to lymph nodes between the breasts. It may also help doctors plan the best treatment.

PURPOSE: This clinical trial is studying how well thoracoscopic sentinel lymph node biopsy finds sentinel lymph nodes that are located between the breasts in patients with stage I or stage II breast cancer.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Miami; University of Miami Sylvester Comprehensive Cancer Center
• Treatments: Technetium Tc 99m Sulfur Colloid

Criteria

DISEASE CHARACTERISTICS:

• Histologically confirmed breast cancer

• Stage I or II disease (T1-T2, N0, M0/MX disease)

• No chest wall invasion by tumor (T3 disease)

• Medially or centrally located lesion

• No multicentric disease

• Multifocal disease allowed

• No clinically positive axillary nodes

• No enlarged internal mammary nodes by CT scan

• Hormone receptor status not specified

PATIENT CHARACTERISTICS:

• Male or female

• Menopausal status not specified

• American Society of Anesthesiologists (ASA) physical status classification 1-2

• Not pregnant or nursing

• Negative pregnancy test

• No other concurrent known, invasive malignancy

• No known chronic pulmonary disease

• No known allergy to methylene blue or isosulfan blue

PRIOR CONCURRENT THERAPY:

• No prior thoracic or cardiac surgery

• No prior ipsilateral chest tube placement

• Contralateral chest tube placement allowed

• No prior neoadjuvant chemotherapy

• No prior radiotherapy to the mediastinum