Thyroid Hormone Replacement for Subclinical Hypothyroidism and Chronic Heart Failure (ThyroHeart-CHF)
Status:
Unknown status
Trial end date:
2019-02-01
Target enrollment:
Participant gender:
Summary
Based on accumulating evidence showing that hypothyroid status is associated with poor
prognosis among heart failure (HF) patients, the study is designed to evaluate whether
replacement treatment with levothyroxine could have beneficial effects on patients with HF
and subclinical hypothyroidism. The study is a prospective, randomized, parallel-group trial
to assess the efficacy and safety of levothyroxine replacement on evidence-based HF standard
therapy in stable chronic heart failure patients with subclinical hypothyroidism.
Phase:
Phase 4
Details
Lead Sponsor:
Chinese Academy of Medical Sciences, Fuwai Hospital
Collaborators:
Henan Provincial Hospital Henan Provincial People's Hospital The First Hospital of Hebei Medical University The Luhe Teaching Hospital of the Capital Medical University Tianjin Medical University Second Hospital