Thyroid Replacement Therapy in Patients With Subclinical Hypothyroidism

• Status: Recruiting
• Trial end date: 2021-10-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this experiment is to compared the changes of thyroid function, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody, thyroid magnetic resonance T1-mapping and various metabolic indexes from baseline to the end of treatment (after the thyroid function had been normal for more than three months)

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Chao Yang Hospital

Criteria

Inclusion Criteria:

• Men or women between the ages of 18 and 75;

• Diagnostic criteria for mild subclinical hypothyroidism :TSH>10mIU/L, thyroxine and free thyroxine levels were normal

• Positive thyroglobulin antibody and/or Thyroperoxidase antibody

• No previous use of drugs affecting thyroid function

Exclusion Criteria:

• The contraindications indicated in the Chinese instructions of the drug

• Liver function impairment

• Renal function impairment

• Claustrophobia

• Mental disorders