Titrated Oral Misoprostol Compared to Vaginal Dinoprostone for Induction of Labor

• Status: Unknown status
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

To test the safety and efficacy of titrated oral misoprostol compared to vaginal dinoprostone for labor induction.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ain Shams University
• Treatments: Dinoprostone; Misoprostol

Criteria

Inclusion Criteria:

• Single vertex presentation.

• Gestational age > 37 weeks calculated from last menstrual period or U/S scanning.

• Bishop score <8 .

• Not in labor.

• Reassuring fetal heart rate (CTG for 20 min on the day of induction).

• Valid indication for Induction of labor.

Exclusion Criteria:

• Gestational age <37 weeks.

• Patients with rupture of membranes.

• Previous uterine scar.

• Fetal malpresentation.

• Multiple pregnancy.

• Significant antepartum hemorrhage

• Uncontrolled DM.

• Severe Pre-eclampsia or Eclampsia

• If there are contraindications to receive the drugs, e.g. allergy, history of severe asthma,…..etc.