Overview

To Demonstrate the Superiority of IMP (0.3% and 1% OPA-15406 Ointment) Versus the Vehicle in Pediatric Patients With AD

Status:
Not yet recruiting
Trial end date:
2024-02-28
Target enrollment:
0
Participant gender:
All
Summary
A multicenter, randomized, double-blind, vehicle-controlled, parallel group trial to demonstrate the superiority of 0.3% and 1% OPA-15406 ointment to vehicle in pediatric subjects with AD. This trial consists of the 0.3% OPA-15406 group, the 1% OPA-15406 group, and the vehicle group.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Otsuka Beijing Research Institute
Criteria
Inclusion Criteria:

1. Sex: Either male or female. Age: 2 to 14 years, inclusive (at time of obtaining
informed consent).

2. Diagnosis of AD based on the criteria of Hanifin and Rajka (see Appendix 1).

3. Atopic dermatitis affecting ≥5% to ≤40% of BSA (excluding scalp) at the screening and
baseline visit.

Exclusion Criteria:

1. Subjects who defined as AD or contact dermatitis rapid deterioration, within 28 days
prior to the baseline visit.