To Evaluate if Multiple Doses of Ketoconazole Change the Blood Concentration of YM150 (Darexaban)
Status:
Completed
Trial end date:
2010-03-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to determine the effect of ketoconazole on the blood
concentrations of darexaban and its metabolites (drug degradation products). The secondary
objective of the study is to evaluate the safety and tolerability of a single dose of
darexaban alone and when administered together with ketoconazole.