Overview

To Evaluate the Effect of Glibenclamide in Reducing Brain Edema of TBI

Status:
Recruiting
Trial end date:
2022-10-01
Target enrollment:
Participant gender:
Summary
Brain edema is one of the main mechanisms of secondary brain injury and one factor in the prognosis of traumatic brain injury . The clinical study of glibenclamide in the treatment of brain edema after traumatic brain injury is designed to evaluate whether glibenclamide treatment can improve the blood NSE and S100β levels of severe traumatic brain injury , so order to explore the efficacy and adverse effects of this drug in the treatment of traumatic brain injury .
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Beijing Tiantan Hospital
Collaborator:
Beijing Tongren Hospital
Treatments:
Glyburide