To Evaluate the Optimum Dose of Platelet Rich Plasma in Knee Osteoarthritis and Compare Efficacy With Hyaluronic Acid
Status:
Completed
Trial end date:
2016-07-10
Target enrollment:
Participant gender:
Summary
Randomized, Double-blind, 12-month, placebo-controlled study was conducted on 100 outpatients
. Intervention platelet rich plasma( PRP) prepared from 60 ml of blood by adding novel step
of filtration to manual centrifuge step to achieve 7 times concentration. the efficacy was
compared with administration of hyaluronic acid. Subjective Womac scores ,6 min pain free
walking distance as well objective assessments MRI ,synovial fluid assessments were made out
.Absolute counts of platelets as dose was evaluated to be effective in alleviating symptoms
in early knee OA.