To Evaluate the Renal Tubular Function Pre and Post Nephrectomy in Living Donors

• Status: Withdrawn
• Trial end date: 2019-04-26
• Target enrollment: 0
• Participant gender: All

Summary

The overall goals of this study are to demonstrate the change in renal tubular function in living donors pre and post nephrectomy at 6 months.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Kansas Medical Center
• Treatments: Deamino Arginine Vasopressin

Criteria

Inclusion Criteria:

• Adult ≥18 years of age, who has been evaluated and approved as a potential living donor by the multi-disciplinary committee. All donors undergo a standard medical, social, and psychological pre- donation assessment

• Only patients who are able to sign their own consent form may be included in this study.

• Subjects must be able and willing, in the investigator's opinion, to complete all study requirements.

Exclusion Criteria:

• Subjects denied for donation for any medical, social or surgical reason to be living donor.

• Patients who are contraindicated or relatively contraindicated for DDAVP: a. patients with von Willebrand disease; b. Patients with habitual or psychogenic polydipsia; c. Patients with coronary artery insufficiency and/or hypertensive cardiovascular disease; d. Patients with conditions associated with fluid and electrolyte imbalance, such as cystic fibrosis, heart failure, and renal disorders; e. Patients predisposed to thrombus formation