To Investigate the Clinical Efficacy of an Experimental Toothpaste

• Status: Withdrawn
• Trial end date: 2009-12-10
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to evaluate the effect of an experimental toothpaste on maintaining gingival health over a 24 week period measured through modified gingival index, bleeding, plaque, and plaque bacteria. Prior to commencing study treatment, subjects will undergo a dental prophylaxis followed by a 2 week period of oral hygiene instruction and weekly professional tooth cleaning to bring the subjects to their optimum gingival health prior to commencing study treatment.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: GlaxoSmithKline
• Treatments: Fluorides

Criteria

Inclusion Criteria:

• Healthy subjects aged 18 years and older

• A minimum of 20 permanent gradable teeth

• For baseline eligibility, subjects must have a minimum Modified Gingival Index score of 1.5-2.3.