Overview

Tofacitinib for Inflammatory Eye Disease

Status:
Active, not recruiting
Trial end date:
2021-04-04
Target enrollment:
Participant gender:
Summary
Non-infectious inflammatory eye disease, such as uveitis and scleritis, is a chronic, auto-immune process that leads to vision loss. While steroids are effective in the short term, the side-effect profile of chronic steroid use necessitates the identification of effective steroid-sparing therapies. Tofacitinib is a small molecule that inhibits the signaling pathways of multiple inflammatory cytokines. The investigators plan to evaluate whether tofacitinib may have efficacy for patients with uveitis and / or scleritis.
Phase:
Phase 2
Details
Lead Sponsor:
Washington University School of Medicine
Treatments:
Tofacitinib