Tolerability and Analgesic Efficacy of Loxapine in Patients With Refractory, Chemotherapy-induced Neuropathic Pain
Status:
Terminated
Trial end date:
2017-07-21
Target enrollment:
Participant gender:
Summary
Loxapine is an antipsychotic drug approved for the treatment of schizophrenia in several
countries including the United States. In animal studies in mice, loxapine reduced
neuropathic pain. Hence, in a proof-of-principle and dose-escalating study the tolerability
and analgesic efficacy of loxapine will be evaluated in patients with neuropathic pain.