Overview

Tolerability and Efficacy of Artemether-Lumefantrine Versus Artesunate + Amodiaquine in Zanzibar

Status:
Completed
Trial end date:
2003-02-17
Target enrollment:
Participant gender:
Summary
The primary objective of the study was to determine PCR corrected cure-rates up to day 42 in children with uncomplicated malaria, treated with either Artesunate + Amodiaquine or Coartem®. Secondary objectives were to determine safety and possible selection of mutations related to the resistance of the tested drugs.
Phase:
Phase 4
Details
Lead Sponsor:
Professor Anders Björkman
Collaborators:
World Health Organization
Zanzibar Malaria Control Programme
Treatments:
Amodiaquine
Artemether
Artemether-lumefantrine combination
Artemether, Lumefantrine Drug Combination
Artemisinins
Artesunate
Lumefantrine