Tolerance and Pharmacokinetics With Capecitabine 5 Out of 7 Days Regimen
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Standard administration of capecitabine use a 14 days administration. Routine practice in
several intitution leads to use a 5 out of 7 days regimen, with less toxicity.
Purpose : to compare the pharmacokinetics of capecitabine, administered 5 days out of 7, as
compared to the standard administration (14 days out of 21). The second end point is to
compare toxicity with either regimen.
Method : Randomized study with two groups : one with standard administration , the second
with 5/7 days regimen