Tongue Exercises and Reflux Therapy for Upper Airway Resistance Syndrome

• Status: Withdrawn
• Trial end date: 2007-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Tongue exercises are described to improved snoring and acid reflux symptoms. Acid reflux treatment has been found to improve obstructive sleep apnea to a limited degree. Upper airway resistance syndrome is caused by resistance to breathing, leading to multiple respiratory event related arousals, leading to daytime fatigue and other various physical ailments. Tongue base or retrolingual collapse is implicated in upper airway resistance syndrome. We will measure sleep quality and quality of life indices before and after treatment for subjects that undergo tongue exercises only, acid reflux treatment only, and those that undergo both treatments.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: West Side ENT
• Treatments: Omeprazole

Criteria

Inclusion Criteria:

• men and women ages 18 to 45

• supine Park tongue position 3+ or greater

• tonsil size 2 or less

• Mueller's 2+ or less

• Friedman Stage II/III

• BMI ≤ 30

• Symptoms of sleep apnea or UARS lasting for > 3 months: excessive daytime sleepiness, OR two of the following:

• Choking or gasping during sleep

• Recurrent awakenings from sleep

• Unrefreshing sleep

• Daytime fatigue

• cold extremities

• inability to sleep supine

• irritable bowel syndrome / GERD / bloating

• low blood pressure

• orthostatic intolerance

• AHI of < 5, and RDI > 10 (polysomnogram within 1 year of entry date)

Exclusion Criteria:

• Significant nasal obstruction

• Prior pharyngeal surgery

• History of radiation to the head and neck

• Dysmorphic facies or craniofacial syndrome

• ASA class IV or V

• Major depression or unstable psychiatric disorder

• Contraindications to taking Omeprozole

• Pregnancy

• Illiteracy (unable to complete required forms)

• No phone # or mailing address, or plans to change in 3 month period

• Any further upper airway surgery within three month period