Toothpastes With Thermal Water for Oral Health

• Status: Active, not recruiting
• Trial end date: 2023-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to compare the effect of toothpastes containing thermal water of Castera-Verduzan with 1450 ppm fluoride and without fluorinated derivatives on oral hygiene, gingivitis, and dentin hypersensitivity in young adults.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: I.M. Sechenov First Moscow State Medical University
• Treatments: Fluorides

Criteria

Inclusion Criteria:

• aged between 20-25 years

• signed an approved Informed Consent Form, authorizing the participation in the trial and the use of the results of the trial for educational purposes and for the publication

• the diagnosis of gingivitis stated clinically

• at least one tooth with the diagnosis of dentin hypersensitivity stated clinically

Exclusion Criteria:

• medical and pharmacotherapeutic histories that may compromise the protocol (pregnancy or breastfeeding, psychiatric disorders, allergies to toothpastes ingredients, eating disorders)

• systemic conditions that are etiologic to dentin hypersensitivity (e.g., chronic acid regurgitation)

history of chemotherapy or radiotherapy

• taking antibiotic, anti-inflammatory, or anti-coagulant medications 4 weeks prior to or after the baseline visit

• oral mucosa pathology

• periodontal surgery in the preceding 3 months

• orthodontic appliance treatment within previous 3 months

• teeth or supporting structures with any other painful pathology or defects

• taking any other agents for DH management 4 weeks prior to or after the baseline visit

• extensively restored teeth and those with restorations extending into the

cervical area

• dental bleaching within previous 3 months

• subject withdrawal of consent

• subject is not compliant with study procedures

• adverse Event that in the opinion of the Investigator would be in the best interest

of the subject to discontinue study participation