Topical Intra-Oral Ketoprofen for Migraine Prevention

• Status: Completed
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Intra-Oral Topical Ketoprofen gel, applied to a branch of the trigeminal nerve, has been shown to prevent migraines when used once daily for 3 months in open label studies. This is a randomized, double-blind, placebo controlled phase III prevention trial to determine safety and efficacy.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Behar, Caren, M.D.
• Treatments: Ketoprofen

Criteria

Inclusion Criteria:

• IHS Migraine with or without aura

• 18 y.o. or older

• at least 4 migraines per month

Exclusion Criteria:

• pregnancy

• other headache conditions

• chronic daily headache

• allergy or sensitivity to NSAIDs other severe illnesses