Topical Minoxidil Versus Topical Glyceryl Trinitrate in Treatment of Chronic Anal Fissure

• Status: Completed
• Trial end date: 2019-09-30
• Target enrollment: 0
• Participant gender: All

Summary

This randomized trial aims to compare two topical treatments in the treatment of chronic anal fissure: minoxidil gel and glycreyl trintrate cream. The endpoint of the study is the duration of healing of anal fissure whereas secondary endpoints include adverse effects of each treatment and recurrence of anal fissure

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mansoura University
• Treatments: Minoxidil; Nitroglycerin

Criteria

Inclusion Criteria:

• Patients of both genders presenting with chronic anal fissure of more than 6 weeks in duration

• Ageing between 18 and 65 years old.

Exclusion Criteria:

• Pregnant patients.

• Patients with recurrent anal fissure after previous sphincterotomy.

• Patients with coexisting anorectal diseases or inflammatory bowel diseases.