Topical Morphine for Stomatitis-related Pain Induced by Chemotherapy
Status:
Completed
Trial end date:
2014-01-01
Target enrollment:
Participant gender:
Summary
Stomatitis/oral mucositis is a common side effect to chemotherapy. Stomatitis is often
associated with painful ulcers in the mouth. The study hypothesis is that morphine
administrated as a mouthwash can relieve stomatitis-related pain by a local analgesic effect.
The purpose of this study is to test the analgesic effect of a morphine mouthwash versus
morphine injections or placebo (no active drug) in children/adolescents with stomatitis
related to chemotherapy. Besides the investigational drugs (morphine mouthwash and morphine
injections) the children/adolescents receive a standardized analgesic treatment for
stomatitis-related pain.