Overview

Topical Phenylephrine Solution in Preventing Oral Mucosa in Bone Marrow Transplant Patients Receiving Cyclophosphamide and Total Body Radiation Therapy

Status:
Terminated

Trial end date:
2017-01-25

Target enrollment:

Participant gender:

Summary

This phase I/II trial studies the safety of topical phenylephrine solution and to see how well it works in preventing oral mucosa (mouth sores) in bone marrow transplant patients receiving cyclophosphamide and total body radiation therapy. Topical phenylephrine solution may prevent or lessen the severity of oral mucosa in patients receiving cyclophosphamide and total body radiation prior to undergoing a bone marrow transplant.

Phase:

Phase 1/Phase 2

Details

Lead Sponsor:

University of Wisconsin, Madison

Collaborator:

National Cancer Institute (NCI)

Treatments:

Cyclophosphamide
Oxymetazoline
Pharmaceutical Solutions
Phenylephrine