Overview Topical-RAPA Use in Inflammation Reversal and Re-setting the Epigenetic Clock Status: Active, not recruiting Trial end date: 2022-12-01 Target enrollment: Participant gender: Summary Topical Rapamycin ointment will be applied to participant forearms to test whether epigenetic changes in the skin are elicited. Phase: Early Phase 1 Details Lead Sponsor: The University of Texas Health Science Center at San AntonioCollaborator: National Institute on Aging (NIA)Treatments: PetrolatumSirolimus