Overview

Topical Ruxolitinib Lichen Planus

Status:
Completed
Trial end date:
2020-08-25
Target enrollment:
Participant gender:
Summary
To evaluate the safety and efficacy of INCB018424 PHOSPHATE CREAM in cutaneous LP as assessed by the change in Physician Global Assessment (PGA), Body Surface Area (BSA), Index Treatment and Control Lesion by Clinical Assessment Scale of Severity for Index Lesion Signs and Symptoms (CAILS) score, Pruritus Numerical Rating Scale (NRS), and Skindex-16. To predict responses through the identification of unique biomarkers of LP at week 0 and utilizing RNA sequencing on responsive and non-responsive tissue at week 4.
Phase:
Phase 2
Details
Lead Sponsor:
Aaron R. Mangold