Topical Tranexamic Acid Use on Granulating Wounds Following Mohs Micrographic Surgery

• Status: Recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Bleeding after Mohs micrographic surgery for skin cancer is a low risk complication that can occur. This study aims to determine the effect of a drug, often used to reduce bleeding, called tranexamic acid when applied topically to the skin wound after surgery.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Missouri-Columbia
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• All adult (18 years or older) patients presenting for Mohs micrographic surgery (MMS) for the treatment of melanoma or nonmelanoma skin cancer (NMSC) with a wound that will be healing by granulation

Exclusion Criteria:

• Patients must not be pregnant or breastfeeding.

• Patients must not have a known allergic reaction or sensitivity to TXA

• Patient must not have an international normalized ratio (INR) out of therapeutic range if on warfarin.