Topical Tranexamic Acid Versus Topical Vitamin C With Microneedling in Periorbital Hyperpigmentation; Comparative Study

• Status: Completed
• Trial end date: 2020-03-15
• Target enrollment: 0
• Participant gender: All

Summary

Both vitamin C 20% and tranexamic acid 5mg/ml combined with microneedling were used for treatment of periorbital hyperpigmentation in a comparative pattern and both resulted in significant improvement of periorbital hyperpigmentation by dermoscopic and clinical evaluation with no statistically significant difference between them in addition to improvement of patients' visual analogue score (VAS) and dermatology life quality index (DLQI).

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kasr El Aini Hospital
• Treatments: Ascorbic Acid; Tranexamic Acid; Vitamins

Criteria

Inclusion Criteria:

• both genders.

• age ≥ 18 years.

• pigmentary, vascular and mixed types of dark halos

Exclusion Criteria:

• pregnancy and lactation

• patients who received treatment in the past 3 months

• patients with active dermatologic diseases or history of atopic dermatitis.

• history of allergy to tranexamic acid or vitamin c

• history of keloid or hypertrophic scars

• pure structural type of dark halos, pigmentary demarcation lines