Topical Use of Vancomycin in Reducing Sternal Wound Infection in Cardiac Surgery (SWI Trial)

• Status: Terminated
• Trial end date: 2019-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research is to determine if using the antibiotic vancomycin as a preventative topical (on the surface of the skin) treatment during open-heart surgery will reduce the risk of developing a sternal wound infection.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Alberta
• Treatments: Vancomycin

Criteria

Inclusion Criteria:

• Able to sign Informed Consent and Release of Medical Information Form

• Age ≥ 18 years

• Undergoing cardiac surgery with complete sternotomy (including re-operations)

Exclusion Criteria:

• Evidence of active infection (any culture positive or blood positive infection)

• Undergoing organ transplantation

• Patients with known hypersensitivity to vancomycin

• Pregnant or nursing women

• Mental impairment or other conditions that may not allow participant to understand the nature, significance, and scope of study