Topical and Intravenous Administration of TXA Are Equally Effective in DAA THA
Status:
Completed
Trial end date:
2015-11-01
Target enrollment:
Participant gender:
Summary
Through a randomized controlled trial, we will compare the intravenous administration of
tranexamic acid with the intra-articular application after a total hip arthroplasty through
direct anterior approach.
- RCT, prospective study
- Academic-monocentric study
- Clinical outcome measurements The postoperative blood loss will be the primary outcome.
Secondary outcomes are
1. The rate of perioperative and postoperative blood transfusion
2. The number of blood units transfused
3. The length of hospital stay
4. Perioperative given intravenous isotonic fluid
The Null-hypothesis is that there is no significant difference in postoperative blood loss
between intra-articular and intravenous administration of TXA.