Topiramate Trial for Compulsive Buying

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

It is a double blind controlled study to test the hypothesis that Topiramate is more effective than placebo in the treatment of compulsive buying, during a period of 12 weeks

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Sao Paulo
• Treatments: Topiramate

Criteria

Inclusion Criteria:

• Match criteria for compulsive buying, according to McElroy et al. (1994), confirmed by semi-structured interview modeled after the Schedules for clinical assessment in neuropsychiatry (SCID)

• woman within fertility age have to be already practicing an acceptable contraception method and to be negative at a pregnancy test

Exclusion Criteria:

• illiteracy

• pregnancy and breastfeeding for woman

• previous history of alcohol abuse/dependence with current elevation of liver enzymes, or a present diagnosis of alcohol abuse/dependence

• past or current drug abuse/dependence, except for nicotine

• history of current or past Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders diagnosis of bipolar disorder, schizophrenia, psychosis or any neuropsychiatric condition causing cognitive impairment

• a history of suicide attempt or acute suicide risk

• severe depression indicated by a score higher than 30 at the beck depression inventory

• current participation on psychotherapy or use of pharmacological agent or experimental dispositive for compulsive buying in the past 3 months

• current use of psychotropic drugs, except benzodiazepines

• cardiovascular disease including a history of heart attack, stroke, arrhythmia, cardiac failure in the past 5 years. Uncontrolled high blood pressure.

• chronic or acute renal or liver failure, as well as Retinopathy and thyroidopathy

• a personal or family history of nephrolithiasis

• immunodeficiency

• any blood dyscrasia

• contraindication or allergy to topiramate

• history of seizures

• dont't have a phone number for contact

• live alone and don't have a person that can inform about the shopping behavior